It is outrageous that, although we have been able to expand the frontiers of medicine, we still have people dying from things like infections. What then have we learn from the works of Louis Pasteur and Robert Koch about eliminating dangers of infections?

The germ theory of disease states that infectious diseases are caused by pathogens and getting rid of these microorganisms greatly reduces the chances of someone getting infected.The realization of the deadly effects of microbes and the increasing importance of infection control is placing greater focus on sterilization techniques. While disinfecting reduces these harmful pathogens from surfaces it is sterilization that kills all the microorganisms- beneficial or not.

We have all seen commercials for disinfectants and you would always hear it kills 99.9% of germs 100% of the time. Well it is true. Only what they conveniently forget to mention is that the 0.1% that is still alive is the pathogens- disease carrying microbes so it is important to remember that disinfectants do not eliminate all microorganisms and are used only on inanimate or non living objects.

Furthermore the amount & kind of organisms killed or inhibited not only depend on the kind of microbes but also on the kind of disinfectants used as the best disinfectants won’t work well unless the temperature is just right, concentration of disinfectant is wrong or there is a lot of dirt on the surface. There are basically two kinds of disinfectants in the market. Bactericidal and Bacteriologist. Bactericidal kills the 99.9% microbes while Bacteriostatic inhibits the growth of the microbes.

Sterilization can be achieved using heat, chemical, filtration, irradiation and high pressure processes. The only problem with a few of these methods is that surfaces, instruments and medical devices that had to be sterilized were made from materials that could be destroyed by heat, moisture or chemicals.

The demand for an innovative method of sterilization that would not use heat, moisture or chemicals and yet be effective spurred researches and in the 1950s Ethylene Oxide gas was discovered for sterilizing these sensitive devices but the ETO is a carcinogen which seriously limited its use. The past decade has witnessed tremendous progress in the research and development of effective low temperature sterilization methods. We now have Peripatetic Acid Immersion (which was released in 1988), Ozone Sterilization (which was cleared by FDA in 2003) and the Plasma Sterilization which has proven to be an appropriate alternative sterilization procedure. This sterilization technology based on plasma was patented in 1987 and produced commercially for the American markets in 1993.

Plasma Sterilization uses very low temperature Hydrogen Peroxide gas plasma technology to sterilize surfaces, instruments and devices. The germicidal effects of plasma have been known for decades but it is only recently that we have begun to apply this technology to industry. Medical Personnel were intrigued with The Plasma Sterilizer as it cut out the ideal sterilization time cycle to 45 minutes (the time cycle with the ETO was 16 hours), had improved load humidity management, didn’t need aeration, had better heat distribution, shallow penetration of gas plasma, was safer for use (as there was supposed lack of emission) and money would be saved for the institution.

The gas plasma is generated by removing electrons from a gas to produce charged nuclei and free electrons. It works by ensuring that the plasma heat output (around 45^oC) intensifies the action of the chemical and that there are no toxic residual remains on the sterilized materials.

Nowadays Gas Plasma Sterilization is widely utilized for the sterilization of spores as spores are more tolerant than other microbes. It also has the ability to inactivate endotoxins and lipid A.

There are some really good Gas Plasma Sterilizers being sold commercially today but public opinion show that the widely recognized sterilizer manufacturer is Sterrad. Other notable manufacturers include MoonMed and Tynsol.

The main ingredient used for sterilization is Hydrogen Peroxide (H2O2 which is highly concentrated (approximately 59%). Cellulosic materials, such as medical grade papers and autoclave pouches, neutralize the sterilizing agent by rapidly interacting with the oxidizing agent and its radicals resulting in an aborted cycle. What this means invariably is that we should watch the kind of materials that come in contact with the sterilizing agent during the process so there won’t be inadequate Sterilant concentration.

Gas plasma sterilizer has a shallow penetration depth of approximately 10–20nm so it is easy to achieve a sterility assurance level of 10^-6 which means the gas plasma sterilization only kills one layer of bioburden.

Plasma will have important applications in medical and industrial settings in the future which mean Plasma Sterilization methods will require further research and investigation. The future success of this technology may depend on close collaboration between microbiologists and physical chemists.

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VERTICAL AUTOCLAVE TOP LOADING WITH NEW LID DESIGN

Model : MO-GR 60/85/110

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 Model : MO-MOST-T-18/24/45/60/80 B Class 

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Model:MO-TMQ.C-50/80 series

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Proper sterilization of surgical instruments and equipment for patient care and surgery is a critical aspect. Plasma sterilization is a new technique for sterilizing certain products without the disadvantages you get with gas sterilization methods.

see also: What is plasma sterilizer?

Plasma sterilization is an alternative to steam sterilization for sterilizing those easily corroded products used in surgery such as clamps, implants, holding instruments, cutting instruments, hemostatic forceps, retractors and others. All these instruments as well as other equipment used in surgery must be sterilized because of the bacteria trapped inside the instruments from being used on other patients.

Before surgery the instruments that require sterilization are wrapped to assist with handling. Instruments prepared for sterilization must be wrapped or packaged in such a way that their sterility can be maintained. The materials used for packaging must allow the Sterilant to contact the device during the sterilization process but also to protect the device from contamination during handling.

Temperature Sensitive Instruments can be Sterilized

Gas plasma sterilization was developed as an alternative to ethylene oxide and is suitable for temperature-sensitive instruments as it can sterilize at lower temperatures. It isn’t however recommended for items with long tubes as gas penetration can be an issue. The use of gas plasma sterilization is dependent on access to the items being sterilized, and porous materials are also not suited for this method of sterilization as they absorb the hydrogen peroxide before being generated into the active plasma form.

Plasma sterilization offers time-saving advantages for the full range of medical instruments –see some of the sensitive items listed below:

• Reusable devices that come into contact with mucous membranes should receive high-level sterilization. These devices include the likes of reusable anesthesia breathing circuits, flexible endoscopes as well as respiratory therapy equipment.
• Laparoscopic or arthroscopic telescopes on the other hand don’t require disinfection, but need to be sterilized before use every time. Instruments that require sterilization must always first be thoroughly cleaned to reduce organic material such as body fluids.

Time-Saving Plasma Sterilization

Time is life in the medical industry. Reliable sterilization depends on contact of the sterilizing agent with all areas of the item to be sterilized and quickly and effectively too. Selection of the type of sterilization method will always depend on the nature of the item to be sterilized. If you have any doubts or queries about sterilizing a medical device, you can always contact the manufacturer of the product. There are different techniques towards medical device sterilization based on the energy source and microorganism destruction method required. Knowing the right sterilization method for a particular medical device requires careful consideration because the incorrect method can be catastrophic.

Contact the MoonMed Team for any Sterilization questions you may have!!

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While plasma was discovered in 1928 and is the 4th state’ of matter, the idea of plasma sterilization was proposed in the sixties as a good, low toxicity method for the use of medical care staff. Today a plasma sterilizer has potential as an antimicrobial sterilization procedure and is sought after not only in the medical industry, but also in agricultural and other industrial settings. An advantage with a plasma sterilizer is the shallow penetration of gas plasmas which eliminates damage to the material being sterilized.

Scientists have estimated that more than 99% of the matter in the universe exists in the plasma state.  Most stars are filled with plasma, an ionized state of matter similar to gas. Plasma doesn’t have a definite shape, but unlike liquid or gas, its shape can change when under the influence of a magnetic field. In our day-to-day lives, plasma is found in some television screens, in fluorescent light bulbs, in neon signs and it can be made in a laboratory.

Quicker, more Thorough Plasma Sterilization

Plasma sterilization was started in 1968 because of the need to ensure that instruments are properly cleaned to avoid infection. Where ethylene oxide is used to sterilize medical instruments, the cycle can take about 8 to 16 hours. If plasma is used however, the cycle will take about 45 to 75 minutes for both wrapped and dry instruments and devices. After this time the products will be ready for use. One of the benefits about this sterilization type is the lower temperatures of sterilization. Temperatures are maintained at 104-122F or 40-50 C range which helps to ensure the delicate instruments of today are not damaged, gas plasma sterilization is typically used before surgery so as to sterilize the like of implants for instance. Plasma is able to inactivate most pathogens, and today low-pressure plasma sterilizers are commercially offered in the market.

Sterilization that Meets Required Criteria

In the 1st century with burgeoning populations, the risk levels of fungi has been increased in food safety, health and in agriculture, and efficient, long-lasting control tools for contaminants are needed. In modern times, the process of sterilization is becoming more and more complex and the risk of error is increased. Plasma has been researched, tested and explored and satisfies all this criteria for sterilization, and operators of the sterilizer simply selects the desired cycle and sterilization information about the cycle stages are displayed on the touch screen. Many studies have shown that plasma treatment can efficiently inactivate fungi and sterilize crop seeds, human tissues, various instruments foods and paper.

With plasma sterilization, you get low thermal loads, no dangerous toxic agents are used, no follow-up treatments will be necessary and there won’t be any formation of toxic products during sterilization, showing that the plasma sterilizer complies with every requirement expected of it and is a fast and safe way to Sterilize.

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• Product Details
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• Automatic control for process of heating, sterilization and cooling
• 3 programs for instruments, glassware, general items are preset, temperature and time can be setaccording to your requirement.
• LED dynamic display for status, temperature and time.
• Buzzer alarms sound for program end.
• Overheating protection device: system can cut off power if temperature passes over to setting value.
• Automatic control for air intake open and close built- in hot air circulation system to ensure temperature uniformity in the chamber.

 

Technical parameters

– Voltage 220V
– Temperature control range 50 – 250°C
– Accuracy of temperature control ±1°C
– Timing: time can be set by operator according to requirement.

Model	Code	Volume	Chamber Dimension mm	Overall dimension mm	Net weight kgs	voltage	power
MOON-GMQ.C	70J	70L	450x450x350	765x575x 750	70	220V	1.46Kw
MOON-GMQ.C	160J	160L	570x600x500	912X890X755	100	220V	2.06Kw

Coming soon…

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Sliding Door Pulse Vacuum Sterilizer is fully automatic And is designed for the sterilization of biology products, utensils, Aseptic clothes, medical instruments and dressings in fields of biological projects, healthcare, animal health laboratory and the pharmaceutical industry, etc.

The chamber door is an automatic vertical sliding door which seals with compressed air It come with a touch screen which makes the operation easier.

The parameters such as time, temperature, pressure, etc. in the cycle process can be displayed and adjusted on the screen and these parameters can also can be printed by the built-in printer.

The programs are fully automatic after starting and the manual operation is also available.

 

 

The PLC is from SIEMENS which is the process controller and is of the highest quality coupled with the extreme reliability and flexibility.

The vacuum step is completed by pulse vacuum feeding steam several times into the chamber to ensure air removal is completed 99%, to avoid trapped air and to ensure the best result for sterilization.

Chamber and jacket is 6mm made from stainless steel.

The door gasket is made of silicon rubber and it is one piece molding without a joint.

Shelves or loading trolley and transfer trolley is standard accessories.

 

Technical parameters

Rated working pressure:	0.21Mpa
Rated working temperature	132°C
Range of pulse times: Range of time for sterilization: Range of time for drying. Safety valve(chamber & jacket)	O — 99 timesO — 9999 secondsO — 9999 secondsopen pressure: 0.23Mpaclose pressure 0.21Mpa
Pulse vacuum range:  Air exhausted	positive pressure 0.065Mpa—0.09Mpanegative pressure —0.05Mpa— -0.09Mpa>99%(≥ 3 times of pulse vacuum)

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Main features

– Microcomputer control with LCD display and touch buttons
– Temperature, time and running status are displayed and error alarms will sound if there is a problem.
– Water filling, heating, sterilization, exhaust and drying are fully automatic.
– Special positive pressure pulse for exhaust completely eliminates cold air in chamber.
– Heat drying function can reduce humidity residue to less than 3%.
– Steam-water internal circulation system doesn’t need water connection. (They are needed only for models 5070/5090 which need to be connected to the water tap connection to supply the steam generator)
– Chamber heating system heats up quickly with uniform temperature during the pre-heating stage.
– Various programs such as instruments textiles and rubber can be chosen.
– Buzzer will alarm at the end of the cycle.
– Printer is optional and can print the date, time and complete cycle process

Safety devices

– Overheating protection: there is an extra protection to stop any overheating.
– There is an extra protection to avoid any over pressure.
– Door interlock device: The program can only start after the door is closed completely with the electronic door lock. The door cannot be opened if there is pressure in chamber or the power is switched off.
– Short circuit safety device: For alternating current the major loop has a short circuit device. Direct current loop has over voltage protection

Technical parameters

Design pressure: 0.28Mpa

Maximum working pressure: 0.23Mpa

Vacuum degree: -80Kpa

Cycle time: 35—50 minutes

Chamber material: SUS304 stainless steel

Water requirement: Distilled water

Design temperature: 150°C

Sterilization temperature: 121/134°C

Maximum working temperature: 135°C

Technical parameters

Temperature uniformity: ≤±0.5°C

 

Model	VolumeLiters	Chamber Dimensionsmm	Overall dimensions mm (WxHxL)	Voltage	power
MOON-TMQ.C	60	380×500	800x725x520	220V	3.6Kw
MOON-TMQ.C	80	380×700	950x725x520	380V	5.8Kw
MOON-TMQ.C	135	500×700	1000x710x1700	380V	7.3Kw
MOON-TMQ.C	185	500×950	1250x710x1700	380V	8.7Kw

Stainless steel cassette box

Various size stainless steel baskets

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 MOON-PS100 PLASMA GALAXY Series

Plasma Sterilizer

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